This product contains a soluble concentrate containing 480 g/l glyphosate, present as 588 g/l of the potassium salt of glyphosate. DIRECTIONS FOR USE IMPORTANT This information is approved as part of the Product Label. All instructions within this section must be read carefully in order to obtain safe and successful use of this product. Warnings EXTREME CARE SHOULD BE TAKEN TO AVOID SPRAY DRIFT AS THIS CAN SEVERELY DAMAGE NEIGHBOURING CROPS OR PLANTS. DO NOT MIX, STORE OR APPLY ROUNDUP FLEX IN GALVANISED OR UNLINED STEEL CONTAINERS OR SPRAY TANKS. DO NOT leave spray mixtures in tank for long periods and make sure tanks are WELL VENTED. Restrictions A period without rain of at least 6 hours and preferably 24 hours must follow application of ROUNDUP FLEX. Do not spray onto weeds which are naturally senescent, or where growth is impaired by drought, high temperatures, a covering of dust, flooding or frost at, or immediately after application, otherwise poor control may result. Do not spray in windy conditions as drift onto desired crops or vegetation can severely damaged or destroy them. Do not tank-mix ROUNDUP FLEX with adjuvants, pesticides or fertilisers, except as specified in the Compatibility section. After application, large concentrations of decaying foliage, stolons, roots or rhizomes should be dispersed or buried by thorough cultivation before crop drilling. Applications of lime, fertiliser, farmyard manure and pesticides should be delayed until 5 days after application of ROUNDUP FLEX. Weeds controlled ROUNDUP FLEX herbicide controls most emerged grasses and broad-leaved weeds. It is important that all weeds are at the correct growth stage when treated, otherwise some re-growth may occur and this will need re-treatment. Apply ROUNDUP FLEX herbicide once grasses and broad-leaved weeds have emerged and they haveACTIVELY GROWING green leaves. PERENNIAL GRASSES must have full emergence of healthy, green leaf. Common Couch, for example, becomes susceptible at the onset of tillering and new rhizome growth, which usually occurs when plants have 4-5 leaves, each with 10-15 cm of new growth. PERENNIAL BROAD-LEAVED WEEDS are most susceptible around the flowering stage. ANNUAL GRASSES AND BROAD-LEAVED WEEDS should have at least 5 cm of leaf, or 2 expanded true leaves, respectively. In set-aside, annual grasses are best treated at full ear emergence, or before stem elongation. Application during the stem extension phase of annual grasses Black-grass and Brome species on set-aside between the end of April and end of May may result in poor control and require retreatment. BRACKEN should be treated after frond tips are unfurled, but presenescence. OTHER SPECIES - recommendations for specific Areas of Use are given in the Recommendation Tables This product will not give an acceptable level of control of Horsetails Equisetum arvense – repeat treatment will be necessary. Note The effects of treatment on the long-term control of perennial broadleaved weeds have not been investigated. Aquatic ROUNDUP FLEX herbicide controls emerged and floating aquatic weeds including Common Reed, Reed Sweet-grass, Reed Canary-grass and Waterlily. Treat when the weeds are actively growing with full emergence of green leaf, at flowering and before dieback. Best results are obtained from applications Page 6 in the periods from mid-July to mid-August on Water-lilies and mid-August to mid-September on reeds. Following crops Upon soil adsorption the herbicidal properties of ROUNDUP FLEX are lost permitting the drilling of crops 48 hours after application. See the „Recommendation Tables‟ for specific restrictions. PREHARVEST OF WINTER WHEAT, WINTER BARLEY WINTER OATS, SPRING WHEAT, SPRING BARLEY, SPRING OATS, COMBINING PEA, FIELD individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application 7 days before harvest Post planting and preemergence of listed CEREALS, OILSEED RAPE, COMBINING PEAS, VINING PEAS, FIELD BEANS, POTATOES, MUSTARD, LINSEED, SUGAR BEET, SWEDE, TURNIP, BULB ONION, LEEK. Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application Pre-emergence ASPARAGUS Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application Pre-emergence PREHARVEST OILSEED RAPE, LINSEED Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application 14 days before harvest PREHARVEST OF MUSTARD Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application 8 days before harvest All edible crops stubble, all non-edible crops stubble Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application 5 days before drilling or planting the following crop./2 days before the drilling or planting of the following crop or 24 hours before cultivating All edible and non-edible crops destruction, before sowing/planting Maximum individual dose litres product/ hectare Permanent grassland destruction, rotational grassland destruction Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application 5 days before harvest, grazing or drilling APPLE and PEAR ORCHARDS Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application After harvest but before green cluster stage CHERRY, PLUM and DAMSON ORCHARDS Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application After harvest post leaf fallbut before white bud stage Natural surfaces not intended to bear vegetation, permeable surfaces overlaying soil, hard surfaces Maximum individual dose litres product/ hectare Enclosed waters, open waters, land immediately adjacent to aquatic areas Maximum individual dose litres product/ hectare Green cover on land not being used for crop production Maximum individual dose litres product/ hectare total dose litres of product/ hectare/crop/ annum time of application 24 hours before cultivating Other Specific Restrictions Users must consult the appropriate water body Environment Agency/Scottish Environmental Protection Agency before using the product near water and must obtain their agreement before using this product to control aquatic weeds. The maximum concentration of active substance in treated water should not exceed ppm. When applying through rotary atomisers, the spray droplet spectra produced must be of a minimum Volume Median Diameter VMD of 200 microns. Weed wipers may be used in any recommended crop where the wiper or chemical does not touch the growing crop. When using weed wipers, the maximum concentrations used must not exceed the following Weed wiper Mini 13 dilution with water Other Wipers 12 dilution with water . Mixing and spraying ROUNDUP FLEX mixes readily with water and can be applied in spray volumes ranging from 80-400 l/ha using tractor mounted, knapsack, rotary atomisers and hand-held sprayers. Specialised application equipment such as weed wipers and spot gun applicators may be used where indicated. Correctly calibrate all sprayers under field or use conditions prior to application. a Tractor mounted and powered hydraulic sprayers These should be capable of applying accurately 80-400 l/ha within a pressure range of bars 20-35 psi. Half fill the spray tank with clean water, start gentle agitation, and then add the correct amount of ROUNDUP FLEX. Top up the tank with water to the required level. To avoid foaming do not use top tank agitation. Use of a defoamer may be necessary. Medium Volume application 150-300 l/ha Avoid high water volumes >300 l/ha which may lead to run-off from the treated vegetation, resulting in reduced control. Low drift nozzles such as air induction and pre-orifice types producing a medium or coarse spray BCPC definition should be used to minimise the risk of drift. Low Volume Application minimum 80 l/ha Low volume application can be achieved by reducing pressure and the appropriate nozzle selection. Low drift nozzles which produce a medium spray quality BCPC definition should be used to minimise the risk of drift. b Knapsack sprayers Recommended delivery range is 80 - 300 l/ha. Half fill the spray tank with clean water, add the correct amount of ROUNDUP FLEX and top up with water. Fill according to best practice as given on the CPA‟s Voluntary Initiative website When used at a walking speed of 1 metre/second to apply a swath of 1 metre width, most knapsack sprayers fitted with a Lurmark AN or similar nozzle deliver approximately 200 l/ha spray volume or 10 l per 500 m2. To apply l/ha of ROUNDUP FLEX, therefore, use a solution, 150ml ROUNDUP FLEX made up to 10 litres. Similarly, knapsack sprayers fitted with low volume nozzles such as Lurmark AN typically deliver approximately 100 l/ha spray volume. To apply l/ha ROUNDUP FLEX in this case use solution. c Rotary Atomisers Hand-held machines can be used to apply a spray volume of 10-40 l/ha, Herbi and Herbaflex. When rotary atomisers are used to apply ROUNDUP FLEXensure that the droplet diameter falls within the range 200-300 microns for all uses. Stir the correct amount of ROUNDUP FLEX to control the particular target species into the sprayer bottle half filled with clean water. Top up with water, close the top and shake gently to ensure good mixing d Weed Wipers For ropewick applicators use a concentration of 1 part ROUNDUP FLEX to 3 parts of water and add a water-soluble dye if required. Care should be taken to avoid dripping onto wanted vegetation. For new generation weed wipers, use 1part ROUNDUP FLEX to 10 or 20 parts of water or as directed by manufacturer‟s instructions. A list of machines is included in the Company Advisory section at the end of this label. e Spot Gun Applicators Spot gun applicators are for the treatment of individual weeds. Apply 5ml of spray to target weed, using a narrow cone TG-3 or TG-5 nozzle. Boat mounted sprayers For use in aquatic situations. Prepare sprayer as for knapsack sprayers Section b above. Calibrate and spray at the lowest speed possible. Always apply against the direction of any current. Compatibility Do not tank mix ROUNDUP FLEX with adjuvants, pesticides or fertilisers except as advised by Monsanto. For up to date information on compatible products contact Monsanto UK Limited tel 01954 717575. Do not tank-mix ROUNDUP FLEX when using rotary atomiser sprayers. Page 16 For hydraulic sprayers maintain continuous agitation when using ROUNDUP FLEX in tank mixture. For knapsack sprayers mix thoroughly and use immediately when using ROUNDUP FLEX in tank mixture. General Information ROUNDUP FLEX herbicide is an advanced formulation containing glyphosate. ROUNDUP FLEX is taken up by foliage and translocated to underground roots, rhizomes and stolons, providing control of both annual and perennial grasses and broad-leaved weeds. ROUNDUP FLEX is rapidly adsorbed onto particulate matter in soils and water and is quickly degraded by the micro-organisms present in soil and aquatic bottom sediments. Until degraded, the active ingredient in ROUNDUP FLEX, glyphosate, is practically immobile in soils and is, therefore, unlikely to contaminate groundwater. ROUNDUP FLEX is a glyphosate formulation which, having no hazard classification, offers a high standard of operator safety. To maximise the intrinsic safety of ROUNDUP FLEX to operator, consumer and environment, the label recommendations and the DEFRA/HSE/DETR publication "Code of Practice for Using Plant Protection Products” of January 2006, should be adhered to. Symptoms on the weeds Symptoms of treatment are generally first seen 7-14 days, or longer, if growth is slow after spraying. Leaf symptoms take the form of a reddening then yellowing of the foliage and are first seen on the grass weeds but take longer to appear on broad-leaved weeds. Reaction of nettle is slow. For aquatic weed control, on reeds and grasses leaf symptoms usually appear within 14-21 days of spraying in the early autumn. Complete foliage desiccation usually occurs 30-40 days after spraying. At this stage the reeds can be cut and removed. During cold conditions leaf symptoms may not appear before natural dieback but no growth will occur in the season following spraying. Effects of weather See Directions for Use Restrictions. ROUNDUP FLEX will remain efficacious at low but not freezing temperatures however the onset of symptoms will be delayed. A covering of dew may reduce efficacy where run-off occurs. Reduced control is likely where weed growth is impaired by natural senescence, drought, high temperature, a covering of dust, flooding or severe/prolonged frost at, or immediately after application. Weed resistance strategy There is low risk for the development of weed resistance to ROUNDUP FLEX. There are no known cases of weed resistance to glyphosate in UK. Strains of some annual weeds Black-grass, Wild oats and Italian Ryegrass have developed resistance to some herbicides which may lead to poor control. A strategy for preventing and managing such resistance should be adopted. This should include integrating herbicides with a programme of cultural control measures. Guidelines have been produced by the Weed Resistance Action Group and copies are available from the HGCA, CPA, your distributor, crop adviser or product manufacturer Monsanto. Growers are encouraged to implement a weed resistance strategy based on a Good Agricultural Practices and b Good Plant Protection Practices by Following label recommendations The adoption of complimentary weed control practices Minimising the risk of spreading weed infestations The implementation of good spraying practice to maintain effective weed control Using the correct nozzles to maximise coverage Application only under appropriate weather conditions Monitoring performance and reporting any unexpected results to Monsanto UK Ltd Tel 01954 717575